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ACADIA Pharmaceuticals Inc. has announced top-line results from the first pivotal Phase III trial with pimavanserin in patients with Parkinson鈥檚 disease psychosis, or PDP. The study did not meet its primary endpoint of antipsychotic efficacy as measured using the Scale for the Assessment of Positive Symptoms, or SAPS.Pimavanserin met the key secondary endpoint of motoric tolerability as measured using the Unified Parkinson鈥檚 Disease R nike air force1 ating S converse schuhen cale, or UPDRS. Pimavanserin was safe and well tolerated, with the frequency of adverse events generally similar in the pimavanserin and placebo arms. The primary endpoint of the study was the mean change in SAPS scores at day converse chucks 42 compared to baseline for each of the two pimavanserin treatment arms versus placebo. Patients showed marked improvements in the SAPS scores across all study arms.Mean reductions in SAPS scores were 5.9 points in the placebo arm, 5.8 points in the 10 mg pimavanserin arm, and 6.7 points in the 40 mg pimavanserin arm. Statisti KARACHI:Mir Hamza鈥檚 eleven-wicket haul guided UBL to a seven-wicket win over Islamabad on the third day of their fourth round fixture of the Quaid-e-Azam Trophy at the Diamond Ground in Islamabad yesterday.UBl resumed their first innings on 270-6 and added 100 more to their total before being dismissed for 370.Quaid-e-Azam Trophy: Bowlers dominate as Lahore Blues on top against HBLTrailing by 95, Islamabad could only make 142 as Hamza claimed six wickets to give his side a simple 47-run target, which they reached in just 8.2 ove adidas samba adidas rs.Meanwhile, Asad Ali starred with the ball in SNGPL鈥檚 25-run victory over Karachi Whites adidas samba mujer . Chasing 246, Karachi Whites resumed their second innings on 35-1 but were dismissed for 220 as Ali took six wickets and Bilawal Bhatti claimed three.At the Iqbal Stadium in Faisalabad, an unbeaten half-century by Saad Nasim helped Lahore Blues defeat HBL by six wickets. HBL resumed their second innings on 90-9 and took their score to 116 to set La new balance 740 hore Blues 168 for victor
ACADIA Pharmaceuticals Inc. has announced top-line results from the first pivotal Phase III trial with pimavanserin in patients with Parkinson鈥檚 disease psychosis, or PDP. The study did not meet its primary endpoint of antipsychotic efficacy as measured using the Scale for the Assessment of Positive Symptoms, or SAPS.Pimavanserin met the key secondary endpoint of motoric tolerability as measured using the Unified Parkinson鈥檚 Disease R nike air force1 ating S converse schuhen cale, or UPDRS. Pimavanserin was safe and well tolerated, with the frequency of adverse events generally similar in the pimavanserin and placebo arms. The primary endpoint of the study was the mean change in SAPS scores at day converse chucks 42 compared to baseline for each of the two pimavanserin treatment arms versus placebo. Patients showed marked improvements in the SAPS scores across all study arms.Mean reductions in SAPS scores were 5.9 points in the placebo arm, 5.8 points in the 10 mg pimavanserin arm, and 6.7 points in the 40 mg pimavanserin arm. Statisti KARACHI:Mir Hamza鈥檚 eleven-wicket haul guided UBL to a seven-wicket win over Islamabad on the third day of their fourth round fixture of the Quaid-e-Azam Trophy at the Diamond Ground in Islamabad yesterday.UBl resumed their first innings on 270-6 and added 100 more to their total before being dismissed for 370.Quaid-e-Azam Trophy: Bowlers dominate as Lahore Blues on top against HBLTrailing by 95, Islamabad could only make 142 as Hamza claimed six wickets to give his side a simple 47-run target, which they reached in just 8.2 ove adidas samba adidas rs.Meanwhile, Asad Ali starred with the ball in SNGPL鈥檚 25-run victory over Karachi Whites adidas samba mujer . Chasing 246, Karachi Whites resumed their second innings on 35-1 but were dismissed for 220 as Ali took six wickets and Bilawal Bhatti claimed three.At the Iqbal Stadium in Faisalabad, an unbeaten half-century by Saad Nasim helped Lahore Blues defeat HBL by six wickets. HBL resumed their second innings on 90-9 and took their score to 116 to set La new balance 740 hore Blues 168 for victor