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In Nature Methods the group of Albert Heck of Utrecht University introduces a new mass spe nike air forces ctrometer based on Orbitrap鈩?technology. This high-sensitive instrument might play a crucial role in the development and use of therapeutic antibodies.The Heck group, in close collaboration with the research group of Alexander Makarov of Thermo Fisher, the inventor of the Orbitrap analyzer, show that protein assemblies of molecul new balance f眉r damen ar weights over 1 million Da can b dunk nike store e analyzed with very high analytical resolving power and exquisite sensitivity down to detection of single ions.The new mass spectrometer permits a detailed analytical footprint of biologically and medically important proteins.In the fast-growing arena of biopharmaceuticals (e.g. therapeutic antibodies) this new instrument will be especially important both in research & development and in quality control, to enable such molecularly complex biomolecules to be used safely in the clinic.Heck: 鈥淭he impact of the high mass resolving power a Kid Cudi, the rapper who has won an avid fan base for his versatility and sensitivity, has entered treatment after revealing a long struggle with depression and suicidal thoughts.Writing late Tuesday on Facebook, Kid Cudi said he felt ashamed before fans who looked up to him but could not hide the "ragin' violent storm inside my heart at all times."" samba og adidas I checked myself into rehab for depression and suicidal urges. I am not at peace. I haven't been since you've known me," he said.Kanye makes history with streaming-majority number one"If I didn't come here, I would've done something to myself. I simply am a damaged human swimming in a pool of emotions new balance nere everyday of my life," he wrote stanley-cup .His disclosure quickly became a major topic on social media, with the overwhelming majority of people voicing compassion for the rapper whose real name is Scott Mescudi.Kid Cudi said that his upcoming album, Passion, Pain & Demon Slayin', was still on track to come out this month but that he would step back f

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Avidity NanoMedicines has announced the issuance of two new U.S. patents. ARCs鈩?combine the potency and specificity of biologics with a nucleic acid-based payload, representing a breakthrough approach to the targeted delivery of nucleic acid-based medicines.The two new U.S. patents arose out of pioneering work conducted by Professor Mark Davis and colleagues at Caltech and are exclusively licensed to Avidity NanoMedicines.U.S. Patent 8,557,292, entitled "Ca new balance f眉r damen rrier nanoparticles and related compositions, methods and systems," contains broad claims covering the novel nanoparticles and their components, as well as methods for making and using them.U.S. Patent 8,746,999 contain yeezy 700 s broad claims nike high dunk covering both the types of targeting ligands, and the types of nucleic acid payloads in ARCs鈩? as well as methods for making and using them.Together, these two new U.S. patents provide a foundation for the intellectual property portfolio covering the ARC鈩?technology as well as the products enabled by the LAHORE:The 58th All Pakistan adidas campus rose Music Conference is stanley brand under way at the Alhamra Arts Council. The week-long event kicked off on Monday with a demonstration by Sheema Kirmani.On the second day, a contest was held to the test vocals and skills of participants from various educational institutions, featuring age groups under ten, over ten, college new balance pour homme and university students and academies.The contest was held at the open air theatre in Bagh-e-Jinnah. The third day would showcase performances from singers from various classical music families across the country.The fourth and fifth days would feature performances on Folk, classical and light classical music at Alhamra 鈥?the Mall. Prize distribution ceremony coupled with folk and classical performances will be held on the final day on September 24.All Pakistan Music Conference is dedicated for promotion, revival and development of traditional performing arts.Published in The Express Tribune, September 22nd, 2016.

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Urban agriculture is booming, but there鈥檚 often a hidden danger lurking in city soils: lead. Arecent University of Illinois studyshowed universally elevated lead levels in soils across Chicago, an urban ag hotspot.Scientists don鈥檛 know much about how vegetables nike dunkpanda and other crops take up and accumulate lead in real-world settings, butnew U of I researchin dunks Chicago backyard gardens shows tomatoes are likely safe to eat, even when grown in highly lead-contaminated soils.鈥淭here was so little lead accumulation in the fruits, we estimate the average adult male would have to eat almost 400 pounds of tomatoes per we nb ek to reach toxic levels,鈥?saysAndrew Margenot, assistant professor in theDepartment of Crop Sciencesat U of I and co-author on the new study. 鈥淗owever, a lower body-weight child of about 60 pounds would need to eat 鈥榦nly鈥?80 pounds of tomatoes per week 鈥?still quite a bit, but a lower threshold of consumption.鈥滻t鈥檚 good news for urban agriculture, but there鈥檚 a potential caveat for ho BRISBANE:Pakistan coach Mickey Arthur said he doesn鈥檛 want to deprive the spectators a chance to watch Yasir Shah as he is confident the leg-spinner will be fit to face Australia in this week鈥檚 day-night opening Test of a three-match series at the Gabba in Brisbane.Yasir, who was left out of Pakistan's final Test of the recent series in New Zealand, missed last week鈥檚 pink-ball tour match against a Cricket Australia XI in Cairns because of a back injury sustained in training.鈥淚 saw him at the team hotel before I came and he seemed fine,鈥?Arthur told reporters in Brisbane. 鈥淲hich is good because you don鈥檛 w new balance 996 ant to deprive the Australian public the chance to see an unbelievable leg-spinner go about his business. And obviously he is integral to our plans as well.鈥漌ahab Riaz reveals Pakistan鈥檚 鈥榯rump card鈥?against AustraliaPakis campus adidas tan have never beaten Australia in a Test series Down Under and the ability to dismiss their hosts twice in a match will be key to their hopes of adidas campus femme doing so in the upc

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A bacterial species closely related to deadly citru new balance 480 s greening disease is rapidly evolving its ability to infect insect hosts, and possibly plants as well.The newly identified species belongs to Liberibacter, a family of bacteria known to infect several economically important crops. There are nine known Liberibacter species, including one that infects potatoes and three that are associated with citrus greening. Citrus greening, also known as Huanglongbing, is the number one killer of citrus trees worldwide. Though many are working on solutions, there is presently no effective prevention or treatment option on the market. Given its relatives鈥?destructive qualities, UC Riverside scientists set out to understand the ways the new species, L. capsica, genetically resembles ot new balance sneaker her types of Liberibacter. 鈥淎s with new strains of COVID-19, bacteria become variants of concern if their mutations ca air force 1 herren n impact pathogenic or transmissible properties,鈥?said Allison Hansen, UCR entomologist and study lead KARACHI:Saturday was the hottest February day in Karachi in the last 20 years. The mercury shot up to 36.5掳C.Heatwave approaching鈥淭he last time the temperature shot up to 36.1掳 C was on February 25, 1996,鈥?said Pakistan Meteorological Department spokesperson Abdul Rashid. He added that the sudden change in weather has been caused because of the cut-off in sea breeze. This usually adidas campus homme happens when there is a low pressure above the sea, which changes the direction of the air, he explained.The spokesperson said that currently the city is receiving dry land breeze fro adidas campus beige m the north-east direction, whereas the humidity level in the air has decreased to nine per cent. This unex adidas samba mujer pected heat is likely to continue till March 2, he added.Climate change: summer to come too soonGeneral physician Dr Waqar Ahmed advised people to refrain from fizzy drinks and junk food as illnesses, such as flu, are more likely to spread in such climate.Published in The Express Tribune, February 28th, 2016.

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